Wei Chen

Wei Chen

Professor of Pediatrics

University of Pittsburgh

Principal Investigator

My lab focuses on developing statistical and computational methods for the analysis of large-scale biomedical data and applying them to study complex diseases. Collaborating with our colleagues, we use cutting-edge technologies, including bulk and single-cell multi-omics (DNA-seq, RNA-seq, methylation, ATAC-seq, Spatial Transcriptomics) to study human diseases such as childhood asthma and age-related macular degeneration. Chen lab welcomes collaborators and trainees to move science forward. Our lab is generously supported by the National Institute of Health, National Science Foundation, Scleroderma Research Foundation, Helmsley Charitable Trust, University of Pittsburgh, and UPMC.

Recent News

  • 09/2025, Dr. Chen received pediatric discovery award from the Department of Pediatrics for his outstanding publication in translational science.
  • 9/2025 Chen Lab received an R01 from NIAMS with Dr. Torok to integrate spational transcriptomics with histology images for identifying scleroderma subgroups.
  • 8/2025 Chen Lab received a DoD grant with Dr. Torok to study pediatric scleroderma using a multi-omics approach.
  • 8/2025 Congratulations to Xiangyu Ye for receiving the highly competitive finalist for the ASHG trainee award, also with an oral talk at ASHG conference at Boston in Oct.
  • 7/2025 Congratulations to Shivum Telang for receiving the student travel award from the ICIBM conference in Columbus, Ohio.
  • 1/2025 Congratulations to Molin Yue’s work on child asthma endotypes published in JAMA. News report: ABC, NBC, CBS, Washington Post, Post Gazatte, Pitt
  • 12/2024 Haoran Hu was awarded a two-year RAC graduate student fellowship from UPMC Children’s Hospital of Pittsburgh.
  • 11/2024 Xueping’s paper was published by Briefings in Bioinformatics.
  • 10/2024 Chen Lab received a renewal from Scleroderma Research Funding(with Dr. Torok) to continue the study of spatial transcriptomics in pediatric scleroderma patients.
  • 9/2024 Dr. Chen joined the officers of Pittsburgh Chapter, American Association Society as Chapter Representative.
  • 8/2024 Haoran’s paper was published by Nature Communications and selected as a featured article.
  • 5/2024 Dr. Chen co-organized STATGEN 2024 conference in Pittsburgh.
  • 3/2024 Chen Lab received an R01 (with Dr. Duerr) from NIDDK to generate a large-scale trans-ancestry, single-cell multi-omics dataset on CD4 T cells.
  • 2/2024 Molin Yue received the 2024 ATS Abstract Scholarship.
  • 1/2024 Dr. Chen was elected as Secretary of Chinese-American Lung Association (CALA)

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